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KMID : 1143220230660030149
Obstetrics & Gynecology Science
2023 Volume.66 No. 3 p.149 ~ p.160
Pregnancy and COVID-19: past, present and future
Kim Young-Keun

Kim Eui-Hyeok
Abstract
Current evidence suggests that severe acute respiratory syndrome coronavirus 2 infection is associated with anincreased incidence of adverse severe maternal and perinatal outcomes. However, vertical transmission is rare. Themanagement of pregnant women with coronavirus disease 2019 (COVID-19) is similar to that of non-pregnantwomen, and effective treatments, including antiviral therapy, dexamethasone, and prophylactic anticoagulationshould not be withheld during pregnancy.
During the early COVID-19 pandemic period, the management of pregnant women was often delayed until thepolymerase chain reaction (PCR) results came out or due to close contact, even among those without symptoms. Outof concern for the spread of infection, cesarean sections were performed instead of vaginal birth, since infection couldhave led to an increase in maternal and neonatal morbidities. Additionally, if the maternal PCR test was positive, theneonate was quarantined, and despite infectivity decreasing 10 days after symptom onset. It is necessary to ease thestrict measures of infection control in the field of obstetrics.
The presence or absence of maternal COVID-19 symptoms should be identified to stratify the risk, and vaginaldelivery can be attempted in asymptomatic women with low infectivity. With more women being vaccinated safetydata about vaccination is rapidly accumulating and no concerns have been detected. Globally, COVID-19 vaccinesare recommended even during pregnancy. In order to prepare for future pandemics, it is necessary to apply lessonslearned from this pandemic. Policymakers and healthcare leaders must determine efficient and effective strategies forpreserving safe maternal care, even during an ongoing global emergency.
KEYWORD
Pregnancy, COVID-19, Severe acute respiratory syndrome coronavirus 2, Risk factors, Vertical infection transmission
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